Dados do Trabalho

Título

TRENDS AGAINST PENILE PROSTHESIS INFECTIOUS COMPLICATIONS IN DIABETIC PATIENTS: A SYSTEMATIC REVIEW AND META-ANALYSIS

Resumo

Background: penile prosthesis had many developments reducing mechanical and infectious complications. Infection has been a feared complication as it can lead to reoperation, penile shortening and scaring, but there are controversial data about risk factors like diabetes mellitus (DM).
Objectives: to gather wide range information about penile prosthesis infection and complications, summarize the contribution of technique and material improvements; present the current state of device infection and survival and a meta-analysis specially focused on DM contribution to penile prosthesis infection.
Methods: the review was performed with no language or time limitation, in 10 data bases. There were included articles about male population who received a penile prosthesis with no model restriction, with a minimum follow up of one year and that reported outcomes and complications properly.
Results: The mean incidence of infection in studies that included a first implant of penile prosthesis ranged from 0.33 to 11.4%. After several improvements, the general incidence of infection was 3 to 5%, in early 2000, and after coating introduction it decreased to 0.3 to 2.7% in naive patients. Also “no touch” technique and centers of reference with high volume surgeons contributed to reduce infection rates. Meta-analysis showed that diabetes mellitus increases infection with odds ratio of 1.56 (95% CI: 1.12 - 2.044).
Conclusions: Penile prosthesis infection decreased in the last decades due to several improvements, but remains an important cause of reoperation and it is related to decreased prosthesis survival. Meta-analysis indicate that diabetes mellitus increases risk of penile prosthesis infection, but studies are needed to define the contribution of disease treatments and glycemic control

Palavras Chave ( separado por ; )

penile prosthesis; penile implants; outcomes; infection; review; meta-analysis; diabetes mellitus