Dados do Trabalho

Título

CHECK LUNG PROTOCOL: CT LUNG CANCER SCREENING IS USEFUL FOR THE ADJUVANT DIAGNOSIS OF COMORBID DISEASES

Introdução

Introduction and objective: Lung cancer screening (LCS) computed tomography (CT) scan of the chest can save lives by identifying tumors in the early-stage. However, most participants die from comorbid illnesses related to smoking. The CTs performed during the LCS contain information about the smoking-related conditions that are currently not accessed systematically. We have developed a simple chest CT assessment protocol (Check Lung protocol) to assess the six most common smoking-related comorbidities prevalent. This data can increase tracking value with minimal impact LCS programs. The objective is to analyze and quantify the prevalence of the six comorbidities smoking-related chest CT scans acquired during LCS programs.

Casuística e Métodos

Material and methods:​​ Data from 774 subjects who met the inclusion criteria for LCS (age >55 and <80 years, >30 packs of cigarettes/year, current smoker or former smoker within 15 years), were analyzed retrospectively. Using software, we analyzed automatically calcification of coronary arteries (CAC), the area of ​​skeletal muscle (AME), interstitial lung disease (ILD), emphysema, vertebral bone density and liver steatosis.

Resultados

Results and discussion:​ One or more comorbidities were identified in 86.6% of CT of chest [CAC, 41.9%; emphysema, 66.3%; DPI, 32.2%; sarcopenia, 9.9%; Hepatic steatosis 40.7%; osteoporosis, 44.2%]. New diagnoses of cardiovascular disease, emphysema and osteoporosis were performed in 25%, 7% and 46% of cases, respectively.

Conclusões

Conclusion: Access to chest CT acquired during LCS programs using the protocol Check Lung was able to identify previously undiagnosed illnesses as cardiovascular disease, sarcopenia, emphysema, interstitial lung disease, osteoporosis and steatosis liver. This protocol can facilitate the diagnosis of these comorbidities, promoting the opportunity for prevention and treatment.

Palavras Chave

Tracking; Lung cancer; Comorbidities; TomograKphy computerized.